About - eLife
WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in …
Latest research | eLife
WEBSep 3, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
For Authors: A simpler way to submit to eLife
WEBMar 11, 2019 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
How to measure and evaluate binding affinities | eLife
WEBAug 6, 2020 · Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput technologies and the projected increase in the availability of binding data, we found it especially timely to evaluate the current standards for ...
Research Articles - eLife
WEBOct 2, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
Cell Division: How centrioles acquire the ability to reproduce
WEBMar 8, 2017 · Centrioles are organelles that have two critical functions. In dividing cells, they recruit a collection of proteins (known as pericentriolar material) to form larger organelles called centrosomes that nucleate microtubules and organize the spindle poles during cell division (Fu et al., 2015; Figure 1A) In non-dividing cells, centrioles are involved in the production of cilia, the tiny hair ...
Publishing and peer review at eLife · eLife
WEB2 Peer review. eLife editors - who are all active researchers - discuss new submissions and decide which will be peer reviewed. The criteria used by the editors are discussed in “How and why eLife selects papers for peer review”.. Each peer reviewer is asked to write a Public Review of the article, and to recommend ways in which the authors could improve it.
Magazine - eLife
WEBeLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
The Natural History of Model Organisms: The secret lives of
WEBJun 4, 2015 · D. melanogaster, described by Meigen in 1830, appears to have originated in sub-Saharan Africa (Lachaise et al., 1988).The first out-of-Africa habitat expansion of D. melanogaster is thought to have occurred between 10,000 and 15,000 years ago, when it moved to Europe and Asia (David and Capy, 1988).North America and Australia were colonized more recently (David and Capy, 1988).
Enhancing CRISPR prime editing by reducing misfolded pegRNA
WEBJun 7, 2024 · PE is a versatile gene-editing technology that enables programmable installation of any nucleotide substitution and small insertions/deletions without requiring a DNA donor template or the introduction of DNA double-strand breaks (Anzalone et al., 2020).It utilizes a Cas9 nickase (nCas9)-reverse transcriptase (RT) fusion protein called PE2 and a prime editing guide RNA (pegRNA, Figure 1a).