Brock Purdy had two costly interceptions against the Cardinals, resulting in a disappointing one-point loss for the 49ers.

A marathon Sunday of Week 5 produced plenty of winners and losers, with the 49ers and Bills among the teams sparking concerns ...

Football feature is generating more watch and wager interest as the New Orleans Saints (2-2) tackle the Kansas City Chiefs (4 ...

Daniels, Brian Robinson Jr., Austin Ekeler and Jeremy McNichols ran all over the Browns, combining for 211 yards on 31 ...

Kyler Murray had a long touchdown run in the first quarter and rallied Arizona with two fourth-quarter scoring drives in the ...

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

After the 49ers blew another game in the 4th quarter to an NFC opponent, the team was dealt another blow as Jake Moody ...

NFL legend Tom Brady recalled facing San Francisco 49ers quarterback Brock Purdy during his first career start in Week 14 of ...

Donte Whitner explained why Jordan Mason isn't at fault for Brock Purdy's game-ending interception in the 49ers' 24-23 loss ...

The game against the Arizona Cardinals marked the second time this season that San Francisco (2-3) blew a double-digit lead ...

The San Francisco 49ers were thought to be among the favorites to represent the NFC in the Super Bowl for a second straight year, but they haven't ...

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live game updates for the latest news, analysis from ...