The Cardinals beat the 49ers, 24-23, on Sunday afternoon in Santa Clara, a win that changed the outlook of their season.

According to the latest odds available at DraftKings Sportsbook, the Seahawks are three-point underdogs at home for this week ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

Tom Brady reminisced on facing San Francisco 49ers quarterback Brock Purdy in 2022, the final season of his career.

Brock Purdy had two costly interceptions against the Cardinals, resulting in a disappointing one-point loss for the 49ers.

It was a good day for the future of the Las Vegas Raiders. Not because of what happened in their matchup against the Denver ...

How to watch Arizona Cardinals vs San Francisco 49ers in NFL Week 5 game today, with time, television channel, streaming ...

Here’s what fans and analysts were saying on Twitter after the 49ers dropped a shocking loss to the Cardinals in Week 5.

SportsLine's model simulated Arizona Cardinals vs. San Francisco 49ers 10,000 times and made its Week 5 NFL picks, ...

One of the top runners in the league will be featured when Jordan Mason and the San Francisco 49ers host the Arizona ...

The 49ers are 2-3 after losing to the Cardinals at home, and now they have to turn around and play the Seahawks in Seattle on ...

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.